Stem cell therapies for heart disease: why do we need bioengineers?

The limited regenerative potential of the heart via cell proliferation or stem cell recruitment is insufficient to compensate for tissue loss after an acute myocardial infarction [1], [2]. Consequently, the increased workload placed on the surviving myocardium often leads to heart failure. Approximately 865,000 Americans per year suffer a myocardial infarction and nearly 4.9 million…